Professor, University of Miami Medical School, Miami, FL


Research Director, AMTL Corp., Miami, FL


Presented at the 45th Annual Congress of the American College of Allergy and Immunology, Los Angeles, CA: November 12-16, 1988 (published – Annals of Allergy)


In order to characterize a negative population with respect to the Alcat Test, a group of healthy young athletes was compared to an age matched group of patients with suspected food sensitivities.


Each group consisted of 25 subjects and the same panel of 9 major dietary components was performed on each subject using the Alcat Test. The healthy, asymptomatic group (A) was selected on the basis of three criteria:


1. Member of the University of Miami Hurricanes Football Team on a nutritionally balanced diet plan

2. No history of food sensitivities

3. Subject fell into the 18-25 age bracket


The patient group (B) consisted of 18 males and 7 females in the same age bracket as group (A).


Reactions were measured as a change in peak area between a control sample and a test sample and were converted to % reaction. Based on a mean of 8.68% from the average of 450 results, a standard deviation of +/- 4,29% was established. From this data, a one-tailed acceptance region was formed consisting of the upper limit of the deviation. The region served as a delimiter for positive result identification. Of the 225 reactions observed for each group.


Group (A) had a total of 5 positive results compared to 47 positive results for Group (B). The mean for Group (A) was 6.56% whereas the mean for Group (B) was 10.80%.


The Alcat Test can discriminate between a healthy (negative) and a patient population group. The mean in a patient group is significantly higher than in a healthy group.