DESCRIPTION: Salivary Hormone Profile for Cortisol and DHEA-S
Cortisol x 5 (optional 6th collection)
DHEA-S
The Adrenal Stress Profile can detect imbalances in the daily circadian secretions of the stress hormones cortisol and DHEA. These imbalances may negatively impact energy levels and lead to other health related issues such as anxiety, chronic inflammatory conditions, chronic fatigue syndrome, depression, insomnia, migraines and infertility.
Since stress and the inflammation it can cause are major underlying factors in so many chronic diseases, checking the circadian deviation from the normal amounts rhythmically secreted can be a window into how well the body is managing this critical component of chronic illness. Both Cortisol and DHEA affect carbohydrate, lipid and protein metabolism, DHEA also serves as the steroidogenic metabolic intermediate in the formation of the sex hormones from progesterone to testosterone and estradiol.
COLLECTION 5 (optional 6th): Saliva collections at specific times over the course of 24 hours. Use saliva collection tubes included in kit.
SPECIMEN STABILITY: Freeze Prior to Shipping - Must be received within 24 hrs (Optimal) to 48 hrs of collection
REJECTION CRITERIA: Samples that are contaminated with blood will give falsely elevated hormone levels
ELISA
Cortisol 82530
DHEA-S 82627
Cortisol in saliva--reference ranges and relation to cortisol in serum. Aardal E, Holm AC. Eur J Clin Chem Clin Biochem. 1995;33(12):927-932. ACTH, and cardiovascular response to a cognitive challenge paradigm in aging and depression. Gotthardt U, Schweiger U, Fahrenberg J, Lauer CJ, Holsboer F, Heuser I. Cortisol, Am J Physiol. 1995;268(4 Pt 2):R865-873. Physiological and pathological variations in saliva cortisol Guechot J, Fiet J, Passa P, et al.. Horm Res. 1982;16(6):357-364. Effects of physiological hypercortisolemia on the regulation of lipolysis in subcutaneous adipose tissue. Samra JS, Clark ML, Humphreys SM, MacDonald IA, Bannister PA, Frayn KN. J Clin Endocrinol Metab. 1998;83(2):626-631 Similarity in saliva cortisol measures in monozygotic twins and the influence of past major depression [In Process Citation]. Young EA, Aggen SH, Prescott CA, Kendler KS. Biol Psychiatry. 2000;48(1):70-74.
