No single food regimen works for everyone. A new study is the most comprehensive effort yet to understand why.
A decade ago, spurred by the success of the Human Genome Project and the affordability of genetic sequencing, scientists began to explore the promise of “nutrigenomics.” Could personalized nutrition, informed by knowledge of an individual’s DNA, help prevent and even treat diet-related diseases?
The results of early studies from Harvard, Stanford and elsewhere were compelling: Genetic differences seemed to predispose individuals to lose different amounts of weight on different types of diets. A multimillion-dollar industry soon sprang up, premised on marketing DNA-based diets. But subsequent research has failed to show any statistically significant difference in weight loss between overweight people who “eat right for their genotype” and those who do not.