DESCRIPTION: Testing of the average telomere length in lymphocytes
Telomere shortening is associated with aging, mortality and age related diseases. Shorter telomeres have been linked to cardiovascular disease, some cancers, osteoporosis, dementia, diabetes, and other chronic degenerative diseases of aging conditions.
The test is designed for anyone interested in promoting optimal health and healthful aging.
COLLECTION Whole blood in sodium citrate tube.
SPECIMEN STABILITY Must be received within 24 hrs (optimal) to 48 hrs of collection.
REJECTION CRITERIA Blood sample is over 48 hours old; hemolyzed, icteric, and lipemic specimens; improper anticoagulant or no anticoagulant used.
Quantitative real-time PCR (qPCR)
Results reported as Telomere Value that is compared to the range of values found to be present in the population of the same age group. Graphic version of the result presentation allows for easier understanding and analysis. Results within the green area (±1SD) and yellow area (±2SD) of the graph are considered to be within normal range. Results in the red area are considered to be outside of the normal range.
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5. PLoS One. 2014 Jan 27;9(1):e87348. doi: 10.1371/journal.pone.0087348. eCollection 2014.The Relationship between Inflammatory Biomarkers and Telomere Length in an Occupational Prospective Cohort Study. Wong JY1, De Vivo I2, Lin X3, Fang SC4, Christiani DC5.
6. Telomeres and telomere dynamics: relevance to cancers of the GI tract. Basu N, Skinner HG, Litzelman K, Vanderboom R, Baichoo E, Boardman LA. Expert Rev Gastroenterol Hepatol. 2013 Nov;7(8):733-48. doi: 10.1586/17474124.2013.848790.
7. Telomeres and their Role in Aging and Longevity.Tzanetakou IP, Nzietchueng R, Perrea DN, Benetos A. Curr Vasc Pharmacol. 2013 Dec 18.